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科研专家:韩守法

 

基本信息:
姓名 韩守法 所在单位: 厦门大学化学生物学系
职称及级别: 教授(高级) 院士选项: 其他
单位性质:: 高校 研究领域: 生物与新医药
学术兼职: 联系电话 获取号码
专家简介:
      博士(University of Toledo,2003) 
      硕士(北京科学院化学研究所,1999) 
      学士(北京大学,1996) 

      博士后(The Scripps Research Institute) 


 研究兴趣:


      基于有机小分子的疾病关联细胞器变化分析与功能调控,糖探针调控炎症反应与肿瘤免疫识别(有机、化学生物学专业招生) 


近期主要代表论著:


      1.Responsive hetero-organelle partition conferred fluorogenic sensing of mitochondrial depolarization; Zhongwei Xue, Hu Zhao, Jian Liu, Jiahuai Han, Shoufa Han*, Chem. Sci. 2017, 8, 1915-1921


      2.Imaging lysosomal pH alteration in stressed cells with a sensitive ratiometric fluorescence sensor, Zhongwei Xue, Hu Zhao, Jian Liu, aJiahuai Han, Shoufa Han*, ACS Sensors. 2017, 2, 436-442


      3.Redirecting immunity via covalently incorporated immunogenic sialic acid on the tumor cell surface, Bijuan Lin, Xuanjun Wu, Hu Zhao, Yunpeng Tian, Jian Liu, Jiahuai Han, and Shoufa Han*, Chem. Sci. 2016, 7, 3737-3741


      4.A carbohydrate-grafted nanovesicle for fluorescence and acoustic imaging of tumors, Xuanjun Wu, Bijuan Lin, Mingzhu Yu, Jiahuai Han, Shoufa Han*, Chem. Sci. 2015, 6, 2002-2009


      5.A sialic acid-targeted near-infrared theranostic for signal activation based intraoperative tumor ablation; Xuanjun Wu, Mingzhu Yu, Bijuan Lin, Hongjie Xing, Jiahuai Han, and Shoufa Han*, Chem. Sci. 2015, 6, 798-803


      6.Optical Tracking of Phagocytosis with an Activatable Profluorophore Metabolically Incorporated into Bacterial Peptidoglycan; Yunpeng Tian, Mingzu Yu, Zhu Li, Jiahuai Han, Liu Yang*, Shoufa Han*, Anal. Chem., 2015, 87, 8381-8386


      7.Lysosomal pH Decrease in Inflammatory Cells Used To Enable Activatable Imaging of Inflammation with a Sialic Acid Conjugated Profluorophore; Mingzhu Yu, Xuanjun Wu, Bijuan Lin, Jiahuai Han, Liu Yang, and Shoufa Han*, Anal. Chem., 2015, 87, 6688-6695


      8.A self-referenced nanodosimeter for reaction based ratiometric detection of hypochlorous acid in living cells,Xuanjun Wu, Zhu Li, Yuhui Yang, Liu Yang, Jiahuai Han and Shoufa Han* Chem. Sci., 2013, 460-467


      9.Rhodamine-deoxylactam functionalized poly[styrene-alter-(maleic acid)] as lysosome activatable probes for intraoperative detection of tumors,Zhu Li, Yunlong Song, Yuhui Yang, Liu Yang, Xiaohong Huang, Jiahuai Han and Shoufa Han*, Chem. Sci., 2012, 2, 2941-2948 


      10.Homomultimeric complexes of CD22 in B cells revealed by protein-glycan cross-linking;  Shoufa Han, Brian E. Collins, Per Bengtson, and James C. Paulson*, Nat. Chem. Biol., 2005,1, 93-97 

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